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Preclinical characterisation of 111 In-DTPA-trastuzumab

British / Immunohistochemistry / Quality Control / Mice / Animals / Radiopharmaceuticals / Trastuzumab / Drug Stability / Indium / Isotope Labeling / Radiopharmaceuticals / Trastuzumab / Drug Stability / Indium / Isotope Labeling

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diccionario de perforación español-ingles

Engineering / Earth Sciences / Analytical Chemistry / Nutrition and Dietetics / Kinetics / Mass Spectrometry / Pharmaceutical Chemistry / Multidisciplinary / Biological Sciences / Caspases / Brain / Humans / Diabetes mellitus / Permeability /  Enzymatic hydrolysis / Calibration / Female / Animals / Male / Ethanol / Tandem Mass Spectrometry / Cost effectiveness / Gas Chromatography / Trypsin / Risk factors / PLoS one / High Performance Liquid Chromatography / Clinical Sciences / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Cattle / Intestines / Caco-2 cells / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Methadone / Hydrazones / Rats / Buffers / Liquid Chromatography / RNA-binding proteins / Reproducibility of Results / Wistar Rats / Risk Factors / Analytical and Bioanalytical Chemistry / Phospholipase D / Analytical Biochemistry / Amino Acid Sequence / Sensitivity and Specificity / Hydrolysis / Vitamin D Deficiency / Drug Stability / Ions / Area Under Curve / Arachidonic Acid / Biochemistry and cell biology / Molecular Sequence Data / Mass Spectrometry / Pharmaceutical Chemistry / Multidisciplinary / Biological Sciences / Caspases / Brain / Humans / Diabetes mellitus / Permeability /  Enzymatic hydrolysis / Calibration / Female / Animals / Male / Ethanol / Tandem Mass Spectrometry / Cost effectiveness / Gas Chromatography / Trypsin / Risk factors / PLoS one / High Performance Liquid Chromatography / Clinical Sciences / High Pressure Liquid Chromatography / CHEMICAL SCIENCES / Cattle / Intestines / Caco-2 cells / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / Methadone / Hydrazones / Rats / Buffers / Liquid Chromatography / RNA-binding proteins / Reproducibility of Results / Wistar Rats / Risk Factors / Analytical and Bioanalytical Chemistry / Phospholipase D / Analytical Biochemistry / Amino Acid Sequence / Sensitivity and Specificity / Hydrolysis / Vitamin D Deficiency / Drug Stability / Ions / Area Under Curve / Arachidonic Acid / Biochemistry and cell biology / Molecular Sequence Data

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Environmental temperature variations cause degradations in epinephrine concentration and biological activity

Epinephrine / Hemodynamics / Animals / Clinical Sciences / High Pressure Liquid Chromatography / Rats / Breakdown / Environmental Temperature / Biological activity / Drug Stability / Hot Temperature / The American / Infusion Pumps / Rats / Breakdown / Environmental Temperature / Biological activity / Drug Stability / Hot Temperature / The American / Infusion Pumps

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Soy polysaccharide as a novel superdisintegrant in sildenafil citrate sublingual tablets: preparation, characterization, and in vivo evaluation

Pharmaceutical Technology / Polysaccharides / Pharmaceutical Chemistry / Humans / Wettability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability / Male / Hardness / Solubility / Phosphodiesterase Inhibitors / Soybeans / Adult / Tablets / Excipients / Drug Stability / Biological Availability

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Carnosine analogues containing NO-donor substructures: Synthesis, physico-chemical characterization and preliminary pharmacological profile

Organic Chemistry / Antioxidants / Humans / Copper / Nitric oxide / Animals / Male / Rats / Reperfusion injury / Vasodilation / Drug Stability / Aldehydes / Carnosine / Animals / Male / Rats / Reperfusion injury / Vasodilation / Drug Stability / Aldehydes / Carnosine

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Sponge-associated microbial Antarctic communities exhibiting antimicrobial activity against Burkholderia cepacia complex bacteria

Engineering / Technology / Principal Component Analysis / Biotechnology / Cystic Fibrosis / Porifera / Biological Sciences / Phylogeny / Humans / Design studies / Volatile Organic Compounds / Animals / Antimicrobial activity / Polymerase Chain Reaction / Phylogenetic analysis / VOC / Anti-Bacterial Agents / Drug Stability / Burkholderia Cepacia Complex / Whole Body / Pathogenic Bacteria / Microbial community / Random amplified polymorphic DNA / Pseudoalteromonas / Porifera / Biological Sciences / Phylogeny / Humans / Design studies / Volatile Organic Compounds / Animals / Antimicrobial activity / Polymerase Chain Reaction / Phylogenetic analysis / VOC / Anti-Bacterial Agents / Drug Stability / Burkholderia Cepacia Complex / Whole Body / Pathogenic Bacteria / Microbial community / Random amplified polymorphic DNA / Pseudoalteromonas

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Sponge-associated microbial Antarctic communities exhibiting antimicrobial activity against Burkholderia cepacia complex bacteria

Engineering / Technology / Principal Component Analysis / Biotechnology / Cystic Fibrosis / Porifera / Biological Sciences / Phylogeny / Humans / Design studies / Volatile Organic Compounds / Animals / Antimicrobial activity / Polymerase Chain Reaction / Phylogenetic analysis / VOC / Anti-Bacterial Agents / Drug Stability / Burkholderia Cepacia Complex / Whole Body / Pathogenic Bacteria / Microbial community / Random amplified polymorphic DNA / Pseudoalteromonas / Porifera / Biological Sciences / Phylogeny / Humans / Design studies / Volatile Organic Compounds / Animals / Antimicrobial activity / Polymerase Chain Reaction / Phylogenetic analysis / VOC / Anti-Bacterial Agents / Drug Stability / Burkholderia Cepacia Complex / Whole Body / Pathogenic Bacteria / Microbial community / Random amplified polymorphic DNA / Pseudoalteromonas

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Physicochemical and biopharmaceutical characterization ofendo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist

Water / Scanning Electron Microscopy / Powder Diffraction / NMR Spectroscopy / Crystallization / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase / Macromolecular X-Ray Crystallography / Molecular Dynamics / Crystal structure / Humans / Liver / Differential scanning calorimetry / Permeability / Pharmaceutical Sciences / Animals / Male / Solubility / Citrus / Intestinal absorption / Caco-2 cells / Rats / X ray diffraction / Carbon Tetrachloride / Molecular Conformation / Flavones / Drug Stability / Crystalline Structure / Drug Induced Liver Injury / Serotonin antagonists / Aspartate Aminotransferases / Alanine Transaminase

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Mammalian Lin-7 Stabilizes Polarity Protein Complexes

RNA / Membrane Proteins / Biological Chemistry / Biological Sciences / Dogs / Cell line / Humans / Mice / Animals / Cell Polarity / CHEMICAL SCIENCES / Protein Complex Detection / Amino Acid Sequence / Base Sequence / Recombinant Proteins / Drug Stability / Tight Junctions / Cell line / Humans / Mice / Animals / Cell Polarity / CHEMICAL SCIENCES / Protein Complex Detection / Amino Acid Sequence / Base Sequence / Recombinant Proteins / Drug Stability / Tight Junctions

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Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid

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Peptide stability in drug development: A comparison of peptide reactivity in different biological media

Rheumatoid Arthritis / Drug development / Pharmaceutical Chemistry / Humans / Liver / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid / Mice / Pharmaceutical Sciences / Animals / Peptides / Cattle / Shell Half-Life / Molecular weight / Amino Acid Sequence / Structure activity Relationship / Drug Stability / Synovial-fluid

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Cyclic endoperoxides of β-carotene, potential pro-oxidants, as products of chemical quenching of singlet oxygen

Biological Sciences / Reactive Oxygen Species / Physical sciences / Beta Carotene / Cytotoxic Activity / Model System / Singlet Oxygen / Drug Stability / Oxidants / Biochemistry and cell biology / Model System / Singlet Oxygen / Drug Stability / Oxidants / Biochemistry and cell biology

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Sponge-associated microbial Antarctic communities exhibiting antimicrobial activity against Burkholderia cepacia complex bacteria

Engineering / Technology / Principal Component Analysis / Biotechnology / Cystic Fibrosis / Porifera / Biological Sciences / Phylogeny / Humans / Design studies / Volatile Organic Compounds / Animals / Antimicrobial activity / Polymerase Chain Reaction / Phylogenetic analysis / VOC / Anti-Bacterial Agents / Drug Stability / Burkholderia Cepacia Complex / Whole Body / Pathogenic Bacteria / Microbial community / Random amplified polymorphic DNA / Pseudoalteromonas / Porifera / Biological Sciences / Phylogeny / Humans / Design studies / Volatile Organic Compounds / Animals / Antimicrobial activity / Polymerase Chain Reaction / Phylogenetic analysis / VOC / Anti-Bacterial Agents / Drug Stability / Burkholderia Cepacia Complex / Whole Body / Pathogenic Bacteria / Microbial community / Random amplified polymorphic DNA / Pseudoalteromonas

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Dendrosomal curcumin nanoformulation downregulates pluripotency genes via miR-145 activation in U87MG glioblastoma cells

Cancer / Cell Cycle / Nanomedicine / Cancer Biology / Nanotechnology / Transcription Factors / Pharmaceutical Chemistry / Apoptosis / Caspases / miRNA / Humans / Glioblastoma / Curcumin / Cell Death / microRNAs / Nanocapsules / Drug Carriers / Drug Stability / Molecular Targeted Therapy / Down-Regulation / Transcription Factors / Pharmaceutical Chemistry / Apoptosis / Caspases / miRNA / Humans / Glioblastoma / Curcumin / Cell Death / microRNAs / Nanocapsules / Drug Carriers / Drug Stability / Molecular Targeted Therapy / Down-Regulation

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Pediocin SA-1, an antimicrobial peptide from Pediococcus acidilactici NRRL B5627: Production conditions, purification and characterization

Thermodynamics / Kinetics / Multidisciplinary / Glucose / Bacteriocins / Antimicrobial activity / Bacteria / Antimicrobial Peptide / Enzyme / Mode of action / Bioreactors / Microbial Sensitivity Tests / Dissolved Oxygen / Amino Acid Profile / Amino Acid Sequence / Drug Stability / Antimicrobial activity / Bacteria / Antimicrobial Peptide / Enzyme / Mode of action / Bioreactors / Microbial Sensitivity Tests / Dissolved Oxygen / Amino Acid Profile / Amino Acid Sequence / Drug Stability

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